anti- STAU1 antibody

Product Description

anti- STAU1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR..

Immunogen: staufen, RNA binding protein, homolog 1 (Drosophila)

Synonyms: STAU

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human esophagus using FNab08312(STAU1 antibody ) at dilution of 1:100

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Image 4: SW480 cells were subjected to SDS PAGE followed by western blot with FNab08312(STAU1 antibody ) at dilution of 1:1000

Gene ID: 6780

Research Area: Metabolism

Uniprot ID: O95793