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Product Description
anti- STIM1 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity)..
Immunogen: stromal interaction molecule 1
Synonyms: D11S4896E, GOK, STIM1, stromal interaction molecule 1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:200-1:2000 IHC: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab08321(STIM1 Antibody) at dilution of 1:200(under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Image 2: .
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08321(STIM1 Antibody) at dilution of 1:500
Gene ID: 6786
Research Area: Metabolism
Uniprot ID: Q13586
