anti- STIM2 antibody

Product Description

anti- STIM2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+)(CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx..

Immunogen: stromal interaction molecule 2

Synonyms: KIAA1482

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, IP, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human spleen tissue slide using FNab08322(STIM2 Antibody) at dilution of 1:200

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab08322(STIM2 Antibody) at dilution of 1:1000

Gene ID: 57620

Research Area: Metabolism

Uniprot ID: Q9P246