anti- STK36 antibody

Product Description

anti- STK36 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Serine/threonine protein kinase which plays an important role in the sonic hedgehog(Shh) pathway by regulating the activity of GLI transcription factors(PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization(PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur(PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function(By similarity). Essential for construction of the central pair apparatus of motile cilia..

Immunogen: serine/threonine kinase 36, fused homolog(Drosophila)

Synonyms: KIAA1278

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human prostate using FNab08335(STK36 antibody) at dilution of 1:50

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Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08335(STK36 antibody) at dilution of 1:300

Gene ID: 27148

Research Area: Metabolism

Uniprot ID: Q9NRP7