anti- SUPT16H antibody

Product Description

anti- SUPT16H antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2(casein kinase II)..

Immunogen: suppressor of Ty 16 homolog(S. cerevisiae)

Synonyms: FACT140, FACTP140

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis using FNab08394(SUPT16H antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08394(SUPT16H antibody) at dilution of 1:300

Gene ID: 6830

Research Area: Metabolism

Uniprot ID: Q9Y5B9