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Product Description
anti- TCF7 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element(5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1..
Immunogen: transcription factor 7(T-cell specific, HMG-box)
Synonyms: TCF1
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08554(TCF7 Antibody) at dilution of 1:600
Gene ID: 6932
Research Area: Metabolism
Uniprot ID: P36402
