anti- TEAD2 antibody

Product Description

anti- TEAD2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds to the SPH and GT-IIC 'enhansons'(5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif..

Immunogen: TEA domain family member 2

Synonyms: TEF4

Reactivity: Human, Mouse

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab08582( TEAD2 Antibody) at dilution of 1:1000

Gene ID: 8463

Research Area: Metabolism

Uniprot ID: Q15562