anti- TEAD4 antibody

Product Description

anti- TEAD4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons'(5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif..

Immunogen: TEA domain family member 4

Synonyms: RTEF1, TCF13L1, TEF3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IP, WB

Recommended dilution:

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Image 4: BGC-823 cells were subjected to SDS PAGE followed by western blot with FNab08584(TEAD4 antibody) at dilution of 1:1500

Gene ID: 7004

Research Area: Metabolism

Uniprot ID: Q15561