anti- TGF-beta 1 antibody

Product Description

anti- TGF-beta 1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease(CED) which known as progressive diaphyseal dysplasia 1(DPD1)..

Immunogen: transforming growth factor, beta 1

Synonyms: CED, DPD1, LAP, TGF beta 1, TGFB, TGFB1, TGFbeta, TGF-beta1, TGF-?1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08638(TGFB1 Antibody) at dilution of 1:200

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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab08638(TGFB1 Antibody) at dilution of 1:600

Gene ID: 7040

Research Area: Metabolism

Uniprot ID: P01137