anti- THOC6 antibody

Product Description

anti- THOC6 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development..

Immunogen: THO complex 6 homolog(Drosophila)

Synonyms: WDR58

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor using FNab08669(THOC6 antibody) at dilution of 1:50

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Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab08669(THOC6 antibody) at dilution of 1:500

Gene ID: 79228

Research Area: Metabolism

Uniprot ID: Q86W42