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Product Description
anti- TMEM59 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3(MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding..
Immunogen: transmembrane protein 59
Synonyms: C1orf8
Reactivity: Human
Tested Application: ELISA, IHC, WB, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab08787(TMEM59 Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab08787(TMEM59 Antibody) at dilution of 1:300
Gene ID: 9528
Research Area: Metabolism
Uniprot ID: Q9BXS4
