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Product Description
anti- TNFR1 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases(aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase..
Immunogen: tumor necrosis factor receptor superfamily, member 1A
Synonyms: CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A
Reactivity: Human, Mouse
Tested Application: ELISA, WB,IHC, FC
Recommended dilution: WB: 1:500-1:5000; IHC: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab08823(TNFR1 Antibody) at dilution of 1:200
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Image 4: HL-60 cells were subjected to SDS PAGE followed by western blot with FNab08823(TNFR1 Antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: P19438
