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Product Description
anti- TRIM25 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784)..
Immunogen: tripartite motif-containing 25
Synonyms: EFP,RING finger protein 147, RNF147, TRIM25, tripartite motif containing 25, Z147, Zinc finger protein 147, ZNF147
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IF, IP
Recommended dilution: WB: 1:200-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200
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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab08976(TRIM25 antibody) at dilution of 1:500
Gene ID: 7706
Research Area: Metabolism
Uniprot ID: Q14258
