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Product Description
anti- TRIP10 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling(By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL..
Immunogen: thyroid hormone receptor interactor 10
Synonyms: Cdc42 interacting protein 4, CIP4, HSTP, Protein Felic, Salt tolerant protein, STOT, STP, TR interacting protein 10, TRIP 10, TRIP10
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recommended dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab08996(TRIP10 antibody) at dilution of 1:2000
Gene ID: 9322
Research Area: Metabolism
Uniprot ID: Q15642
