anti- TXNDC5 antibody

Product Description

anti- TXNDC5 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene..

Immunogen: thioredoxin domain containing 5 (endoplasmic reticulum)

Synonyms: EndoPDI, ER protein 46, ERP46, Hcc 2, PDIA15, Thioredoxin like protein p46, TLP46, TXNDC5, UNQ364

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab09127(TXNDC5 antibody) at dilution of 1:100

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09127(TXNDC5 antibody) at dilution of 1:1000

Gene ID: 81567

Research Area: Metabolism

Uniprot ID: Q8NBS9