anti- UBB antibody

Product Description

anti- UBB antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants..

Immunogen: UBB

Synonyms: Polyubiquitin B, UBB, ubiquitin, ubiquitin B

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab09865(UBB antibody) at dilution of 1:200

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Image 4: SW480 cells were subjected to SDS PAGE followed by western blot with FNab09865(UBB antibody) at dilution of 1:1000

Gene ID: 7314

Research Area: Metabolism

Uniprot ID: P0CG47