anti- UBR2 antibody

Product Description

anti- UBR2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth..

Immunogen: ubiquitin protein ligase E3 component n-recognin 2

Synonyms: BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IF, IHC

Recommended dilution: WB: 1:200-1:2000; IF?1?10-1:100; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab09209(UBR2 Antibody) at dilution of 1:50

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Image 4: BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab09209(UBR2 antibody) at dilution of 1:600

Gene ID: 23304

Research Area: Metabolism

Uniprot ID: Q8IWV8