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Product Description
anti- ULBP2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface..
Immunogen: UL16 binding protein 2
Synonyms: ALCAN alpha, N2DL 2, N2DL2, NKG2D ligand 2, NKG2DL2, RAET1H, UL16 binding protein 2, ULBP2
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09250(ULBP2 antibody) at dilution of 1:400
Gene ID: 80328
Research Area: Metabolism
Uniprot ID: Q9BZM5
