anti- UMPS antibody

Product Description

anti- UMPS antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants..

Immunogen: uridine monophosphate synthetase

Synonyms: OMPdecase, OPRT, OPRTase, UMPS

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab09253(UMPS antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09253(UMPS antibody) at dilution of 1:1000

Gene ID: 7372

Research Area: Metabolism

Uniprot ID: P11172