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Product Description
anti- USP37 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2)..
Immunogen: ubiquitin specific peptidase 37
Synonyms: Deubiquitinating enzyme 37, KIAA1594, Ubiquitin thiolesterase 37, USP37
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000; IP: 1?200-1?2000
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09330(USP37 antibody) at dilution of 1:500
Gene ID: 57695
Research Area: Metabolism
Uniprot ID: Q86T82
