anti- UXT antibody

Product Description

anti- UXT antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription(AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation(PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling(PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC(PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function(PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM(PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region..

Immunogen: ubiquitously-expressed transcript

Synonyms: ART 27, Protein UXT, UXT

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recommended dilution: WB: 1:200-1:1000; IP: 1:200-1:1000

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09353(UXT antibody) at dilution of 1:400

Gene ID: 8409

Research Area: Metabolism

Uniprot ID: Q9UBK9