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Product Description
anti- VPS52 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061)..
Immunogen: vacuolar protein sorting 52 homolog(S. cerevisiae)
Synonyms: ARE1, dJ1033B10.5, DKFZp547I194, RP5 1033B10, SAC2, SACM2L, VPS52
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF, IP
Recommended dilution: WB: 1:200-1:2000?IP: 1:500-1:5000?IHC: 1:20-1:200; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human gliomas using FNab09447(VPS52 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab09447(VPS52 antibody) at dilution of 1:1000
Gene ID: 6293
Research Area: Metabolism
Uniprot ID: Q8N1B4
