anti- VWF, VWFpp antibody

Product Description

anti- VWF, VWFpp antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Von Willebrand factor(vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII(FVIII). Deficiency of vWF results in von Willebrand disease(vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids(aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide(vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region of pre-pro-vWF recognizes von Willebrand antigen 2(75-83 kDa) and pro-vWF(309-320 kDa)..

Immunogen: von Willebrand factor

Synonyms: F8VWF, von Willebrand antigen II, von Willebrand factor, VWD, VWF

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200-1:2000; IHC: 1:100-1:400

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab09466(VWF, VWFpp Antibody) at dilution of 1:200

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09466(VWF, VWFpp antibody) at dilution of 1:500

Gene ID:

Research Area: Metabolism

Uniprot ID: P04275