anti- WDR1 antibody

Product Description

anti- WDR1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins(PubMed:15629458). Enhances cofilin-mediated actin severing(By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions(PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance(By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity(PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension(By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt(PubMed:25792565)..

Immunogen: WD repeat domain 1

Synonyms: Actin interacting protein 1, AIP1, NORI 1, WD repeat containing protein 1, WD repeat domain 1, WDR1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, IP, WB

Recommended dilution: WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab09481(WDR1 antibody) at dilution of 1:100

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Image 4: rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09481(WDR1 Antibody) at dilution of 1:600

Gene ID: 9948

Research Area: Metabolism

Uniprot ID: O75083