Product Description
anti- WEE2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity)..
Immunogen: WEE1 homolog 2(S. pombe)
Synonyms: FLJ16107, WEE1 homolog 2(S. pombe), Wee1 like protein kinase 1B, Wee1 like protein kinase 2, WEE1B, Wee1B kinase, WEE2
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:200-1:2000
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09506(WEE2 antibody) at dilution of 1:500
Gene ID: 494551
Research Area: Metabolism
Uniprot ID: P0C1S8