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Product Description
anti- WRAP53 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage..
Immunogen: WD repeat containing, antisense to TP53
Synonyms: FLJ10385, TCAB1, WDR79, WRAP53
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:1000
Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab09523(WRAP53 antibody) at dilution of 1:100
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Image 4: human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09523(WRAP53 antibody) at dilution of 1:300
Gene ID: 55135
Research Area: Metabolism
Uniprot ID: Q9BUR4
