anti- WTAP antibody

Product Description

anti- WTAP antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724)..

Immunogen: Wilms tumor 1 associated protein

Synonyms: DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:1000-1:10000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human cervical cancer using FNab09530(WTAP antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09530(WTAP Antibody) at dilution of 1:2000

Gene ID: 9589

Research Area: Metabolism

Uniprot ID: Q15007