anti- XPO7 antibody

Product Description

anti- XPO7 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Mediates the nuclear export of proteins(cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus..

Immunogen: exportin 7

Synonyms: Exp7, exportin 7, KIAA0745, Ran binding protein 16, RANBP16, XPO7

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution: WB: 1:500-1:5000

Image 1:

Image 2: .

Image 3:

Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab09551(XPO7 antibody) at dilution of 1:300

Gene ID: 23039

Research Area: Metabolism

Uniprot ID: Q9UIA9