anti- Zyxin antibody

Product Description

anti- Zyxin antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin(ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles..

Immunogen: zyxin

Synonyms: ESP 2, HED 2, ZYX, zyxin, Zyxin 2

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney slide using FNab09765(ZYX Antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of HeLa cells using FNab09765(ZYX Antibody) at dilution of 1:50.

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09765(ZYX antibody) at dilution of 1:1000

Gene ID: 7791

Research Area: Metabolism

Uniprot ID: Q15942