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Antibody

 

How to generate monoclonal and polyclonal antibodies?

Plyclonal are easy to make by immunising a host animal while monoclonals need a sterile lab to merge splenocystes with cell lines that will never die and produce forever monoclonal antibodies mostly mouse splenocytes are used for production. The monoclonals are called clone and have their own name or number.

What is theft of Monoclonal cell lines?

A student or post Doc may take home monoclonal cell lines in carbo ice and store them in a minus 85 freezer for weeks or liquid nirtrogen container called dewar. However the clone stays property of his employer most often a University or Governmnetal Institution. 

The thief cannot sell the antibody producing cell line under the original name. A thrick used by monoclonal cell line thiefs is to give another clone name to the cell. Exacly the same cell lines are circulating under different clona name. QBEND10 CD35 stemm cell marker is an example of an cell line that is available under other names.

How large is the illeagal monoclonal cell line market?

Monoclonal cell line theft in the USA, UK and Europe is costing  10 million of income loss to Universities, estimation 2022 made by Lieven Gevaert, Bio-ir. Gentaur BV.

 Are there lots of cell lines lost by accident?

Monoclonal cell line loss, intenianally when a project stops or accidentially by a bubble in the N2 container is estimated to 1 million USD of income loss to the owners.

 What are the most famouse cell line losses in Belgian research history?

Famous losses are the ULB HPV best monoclonal collection where the freezer was stopped intentionally whe the funding stopped. Unfortunately no monoclonal thiefs had copies of these unique cell lines.

Examples of accidential cell line loss.

  1. The best MIP2 antibody was accidentially lost by KULeuven in 2002
  2. GSK in Rixensart and Johnson and Johnson, Janssens Pharmaceutica in Beerse, UCB Pharma in Braine l'Alleud all losts valualble cell lines due to a N2 liquid Nitrogen problem both in the backup dewar and master dewar.
  3. Orla Proteins is storing cell lines at Gentaur BV in Belgium safe room. Also Gentaur has known a loss of 1 dewar in 2012 due to an air bubble.

What are the most used used applications of antibodies?

Research of immunology includes immunoprecipitation, sandwich ELISA, Western blot, immunofluorescence (IF) microscopy, flow cytometry, receptor neutralization, and cell depletion.

 

  • p14 ARF Antibody

    P300/CBP Antibody

    P300/CBP Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • TBP Antibody

    VDAC1 Antibody

    VDAC1 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • TFEB Antibody TFEB Antibody

    TBP Antibody

    TBP Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • TNF Receptor II Antibody

    Ku70/80 Antibody

    Ku70/80 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • TM16J Antibody TFE3 Antibody

    TNF Receptor II Antibody

    TNF Receptor II Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month...

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  • MED1 Antibody MED1 Antibody

    RhoH Antibody

    RhoH Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • p73 Antibody

    COX IV antibody

    COX IV antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • SNAI2 antibody SNAI2 antibody

    HSP70 antibody

    HSP70 antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • GluR4 Antibody

    GluR8 Antibody

    GluR8 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • GluR2/3 Antibody

    GluR6 Antibody

    GluR6 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • Collagen III Antibody

    GluR4 Antibody

    GluR4 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • Collagen II Antibody

    GluR2/3 Antibody

    GluR2/3 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • 53BP1 Antibody

    Cyclin E2 Antibody

    Cyclin E2 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • PKA CAT Antibody

    53BP1 Antibody

    53BP1 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • IGFBP2 Antibody IGFBP2 Antibody

    SIAH2 Antibody

    SIAH2 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • OR51E2 Antibody

    PKA CAT Antibody

    PKA CAT Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • PTPN22 Antibody PTPN22 Antibody

    TGFBR2 Antibody

    TGFBR2 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • OR4F4/4F5/4F17 Antibody OR4F4/4F5/4F17 Antibody

    OR51E2 Antibody

    OR51E2 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • MAPK7 Antibody HDAC4 Antibody

    PTEN Antibody

    PTEN Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • MYPT1 Antibody

    MMP- 8 Antibody

    MMP- 8 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

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  • Myosin regulatory light chain 2  (Phospho- Ser18)  Antibody

    MYPT1 (Phospho- Thr853) Antibody

    MYPT1 (Phospho- Thr853) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • hnRNP K  (Phospho- Ser284)  Antibody

    MYPT1 Antibody

    MYPT1 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • ANXA2  (Phospho- Ser26)  Antibody

    hnRNP K (Phospho- Ser284) Antibody

    hnRNP K (Phospho- Ser284) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for...

    €0.00
  • hnRPD  (Phospho- Ser83)  Antibody

    Daxx (Phospho- Ser668) Antibody

    Daxx (Phospho- Ser668) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • Caspase 1  (Phospho- Ser376)  Antibody

    ANXA2 (Phospho- Ser26) Antibody

    ANXA2 (Phospho- Ser26) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • ATRIP  (Phospho- Ser224)  Antibody

    hnRPD (Phospho- Ser83) Antibody

    hnRPD (Phospho- Ser83) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • Cyclin C  (Phospho- Ser275)  Antibody

    ATRIP (Phospho- Ser224) Antibody

    ATRIP (Phospho- Ser224) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • VAMP4  (Phospho- Ser30)  Antibody VAMP4  (Phospho- Ser30)  Antibody

    ATF- 4 (Phospho- Ser219) Antibody

    ATF- 4 (Phospho- Ser219) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for...

    €0.00
  • Telomerase  (Phospho- Ser824)  Antibody

    Cyclin C (Phospho- Ser275) Antibody

    Cyclin C (Phospho- Ser275) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for...

    €0.00
  • Cyclin D2  (Phospho- Thr280)  Antibody

    LCK (Phospho- Ser59) Antibody

    LCK (Phospho- Ser59) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • Cyclin H  (Phospho- Thr315)  Antibody

    eIF4B (Phospho- Ser422) Antibody

    eIF4B (Phospho- Ser422) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • CD3

    Gab2 (Phospho- Ser623) Antibody

    Gab2 (Phospho- Ser623) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one...

    €0.00
  • Dematin  (Phospho- Ser403)  Antibody

    Cyclin H (Phospho- Thr315) Antibody

    Cyclin H (Phospho- Thr315) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for...

    €0.00
  • hnRNP K Antibody

    Dematin (Phospho- Ser403) Antibody

    Dematin (Phospho- Ser403) Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for...

    €0.00
  • Daxx  Antibody

    MRLC2 Antibody

    MRLC2 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • ANXA2 Antibody

    hnRNP K Antibody

    hnRNP K Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • hnRPD Antibody

    Daxx Antibody

    Daxx Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • IL- 6R Antibody IL- 6R Antibody

    ANXA2 Antibody

    ANXA2 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • ATF- 4  Antibody

    Caspase 1 Antibody

    Caspase 1 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • Cyclin C Antibody

    ATRIP Antibody

    ATRIP Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • Stathmin 1 Antibody

    ATF- 4 Antibody

    ATF- 4 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • TERT Antibody

    Cyclin C Antibody

    Cyclin C Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • PECAM- 1 Antibody PECAM- 1 Antibody

    Stathmin 1 Antibody

    Stathmin 1 Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • IKK-

    TERT Antibody

    TERT Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • Cyclin D2 Antibody

    LCK Antibody

    LCK Antibody is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without...

    €0.00
  • GCN2  (Phospho- Thr899)  Antibody Caveolin 2  (Phospho- Tyr27)  Antibody

    IKK-

    IKK- is available at Gentaur for Next Week Delivery. Clonality:  Polyclonal Purification:  Protein A & Antigen Affinity Purity:  ≥95% as determined by SDS-PAGE Storage conditions:  Stored at 2℃-8℃ for one month without detectable...

    €0.00