Anti 4-HNE monoclonal antibody (HNEJ2)

Product Description

Anti 4-HNE monoclonal antibody (HNEJ2) is available at Gentaur for Next Week Delivery.

Description:  Reactive oxygen species (ROS) are involved in lipid peroxidation inside the living bodies, and membrane lipids are one of the major targets of ROS. During the peroxidation process, a variery of aldehydes are formed. 4-hydroxy-2-nonenal (4-HNE) is an alpha, beta unsatulated aldehyde that can be formed by peroxidation of omega-6 unsatulated fatty acids such as linoleic acid and arachidonic acid. Especially, 4-HNE formed inside living body is reported to originate from phospholipid-bound arachidonic acid. 4-HNE may be one of the most reliable biomarker of lipid peroxidation.

More Information:  High-power view of colorectal carcinoma cells. Adenocarcinoma (arrows) and nontumorous epithelial cells (star x240). (S. Kondo et al. Free Radical Biology & Medicine 27 pp401-410, 1999)

Assay principle: 

Specifity:  This antibody show almost negligible reactivity with proteins that were treated with other aldehydes, such as 2-nonenal, 2-hexenal, 1-hexanal, 4-hydroxy-2-hexenal,formaldehyde, or glutaraldehyde.

Measuring range: 

Form: Lyophilized Powder (containing 20 µg or 100 µg of IgG)

Antigen: 4-HNE-modified Keyhole Limpet Hemocyanin

Applications:  Immunohistochemistry and western blotting.

Storage:  Less than -20°C for 5 years. When transport, stable at least 7 days at room temperature.

Expiry: 

Required but not provided: 

Remarq:  Popular lipid oxidantion marker.