Anti Hexanoyl-Lysine (HEL) monoclonal antibody is available at Gentaur for Next Week Delivery.
Description: Oxidative damage of lipids caused by reactive oxygen species (ROS) play an important role in some diseases, lesion of cell functions and aging. Aldehydes such as malondi-aldehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) have been reported as one of the advanced lipid peroxidation products. But recently in the earlier stage of lipid peroxidation, 13-hydroperoxyoctadecanoic acid (13-HPODE) is found to be covalently bound to proteins1). Hexanoyl-Lysine adduct (HEL) is a novel lipid hydroperoxide-modified lysine residues. HEL is formed by oxidative modification by oxidized omega-6 fatty acids such as linoleic acid or arachidonic acid. This monoclonal antibody (clone 5H4)is spesific for proteins and peptides containing HEL. Suitable for HEL detection by immunohistochemistry and western blotting.
Specifity: Specific to Hexanoyl-Lys adducts.
Form: Lyophilized power. Containing 10mM PBS(pH7.4), 5% sucrose, 1% BSA and 0.05% Procline 950. 100 µg/mL of IgG.
Antigen: N epsilon hexanoyl-Keyhole limpet hemocyanin (HEL-KLH)
Applications: Immunohistochemistry (Recommended antibody concentration is 2 µg/mL on paraformaldehyde fixed tissue), and ELISA
Storage: Less than -20°C
Required but not provided:
Remarq: Immunohistochemistry, western blotting and ELISA."