Recombinant Human Acid ceramidase (ASAH1)

Product Description

Recombinant Human Acid ceramidase (ASAH1) is available at Gentaur for Next week Delivery.

Gene Name: ASAH1

Alternative Names : Acylsphingosine deacylase N-acylsphingosine amidohydrolase Putative 32KDA heart protein Short name:PHP32

Expression Region : 22-395aa

AA Sequence : QHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW

Sequence Info : Full Length of Mature Protein

Tag Info : N-terminal 6xHis-SUMO-tagged

Theoretical MW : 58.7 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.

Function : Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.

Involvement in disease : Farber lipogranulomatosis (FRBRL); Spinal muscular atrophy with progressive myoclonic epilepsy (SMAPME)

Subcellular location : Lysosome

Protein Families : Acid ceramidase family

Tissue Specificity : Broadly expressed with highest expression in heart.

Paythway :

Uniprot ID : Q13510