Product Description
Recombinant Human Beta-defensin 104 protein (DEFB104A) (Active) is available at Gentaur for Next week Delivery.
Gene Name: DEFB104A,DEFB104,DEFB4;,DEFB104B
Alternative Names : Beta-defensin 4, DEFB-4, hBD-4, Defensin, beta 104,
Expression Region : 27-112aa
AA Sequence : EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 6.0 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 130 mM NaCl
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 0.1-100.0 ng/ml.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Microbiology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. {ECO:0000269|PubMed:11481241}.
Function : Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Beta-defensin family
Tissue Specificity : High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.
Paythway :
Uniprot ID : Q8WTQ1