Recombinant Human Beta-defensin 4A protein (DEFB4A) (Active)

Product Description

Recombinant Human Beta-defensin 4A protein (DEFB4A) (Active) is available at Gentaur for Next week Delivery.

Gene Name: DEFB4A,DEFB102,DEFB2,DEFB4;,DEFB4B

Alternative Names : Beta-defensin 2, hBD-2, Defensin, beta 2, Skin-antimicrobial peptide 1, SAP1

Expression Region : 24-64aa

AA Sequence : GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 4.3 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 130 mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by a chemotaxis bioassay using immature human dendritic cells is in a concentration range of 10-100 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Microbiology 

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Has antibacterial activity. {ECO:0000305}.

Function : Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells

Involvement in disease :

Subcellular location : Secreted

Protein Families : Beta-defensin family, LAP/TAP subfamily

Tissue Specificity : Expressed in the skin and respiratory tract.

Paythway :

Uniprot ID : O15263