Product Description
Recombinant Human C-C motif chemokine 7 protein (CCL7) (Active) is available at Gentaur for Next week Delivery.
Gene Name: CCL7,MCP3,SCYA6,SCYA7
Alternative Names : Monocyte chemoattractant protein 3, MCP-3, NC28, Small-inducible cytokine A7,
Expression Region : 24-99aa
AA Sequence : QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 9.0 kDa
Storage Buffer : Lyophilized from a 0.2 ?m filtered 20 mM PB, pH 7.4, 150 mM NaCl
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Function : Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Intercrine beta (chemokine CC) family
Tissue Specificity :
Paythway : Chemokinesignalingpathway
Uniprot ID : P80098