Product Description
Recombinant Human Ciliary neurotrophic factor protein (CNTF) (Active) is available at Gentaur for Next week Delivery.
Gene Name: CNTF
Alternative Names : CNTF,
Expression Region : 1-200aa
AA Sequence : MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
Sequence Info : Full Length
Tag Info : Tag-Free
Theoretical MW : 22.9 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 150 ng/ml, corresponding to a specific activity of ? 6.7 × 103 IU/mg.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Neuroscience
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Function : CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Involvement in disease :
Subcellular location : Cytoplasm
Protein Families : CNTF family
Tissue Specificity : Nervous system.
Paythway : Jak-STATsignalingpathway
Uniprot ID : P26441