Recombinant Human Desert hedgehog protein (DHH), partial (Active)

Product Description

Recombinant Human Desert hedgehog protein (DHH), partial (Active) is available at Gentaur for Next week Delivery.

Gene Name: DHH

Alternative Names : DHH,

Expression Region : 24-198aa

AA Sequence : II+GPGRGPVG RRRYARKQLV PLLYKQFVPG VPERTLGASG PAEGRVARGS ERFRDLVPNY NPDIIFKDEE NSGADRLMTE RCKERVNALA IAVMNMWPGV RLRVTEGWDE DGHHAQDSLH YEGRALDITT SDRDRNKYGL LARLAVEAGF DWVYYESRNH VHVSVKADNS LAVRAGG

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 19.9 kDa

Storage Buffer : Lyophilized from a 0.2 ?m filtered 10mM PB, pH 6.0, 300mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 15-45 ?g/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Stem Cells

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.

Function : Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.

Involvement in disease : Partial gonadal dysgenesis with minifascicular neuropathy 46,XY (PGD); 46,XY sex reversal 7 (SRXY7)

Subcellular location : Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side, Note=The N-terminal peptide remains associated with the cell surface, SUBCELLULAR LOCATION: Desert hedgehog protein C-product: Secreted, extracellular space

Protein Families : Hedgehog family

Tissue Specificity :

Paythway : Hedgehogsignalingpathway

Uniprot ID : O43323