Recombinant Human Eotaxin protein (CCL11) (Active)

Product Description

Recombinant Human Eotaxin protein (CCL11) (Active) is available at Gentaur for Next week Delivery.

Gene Name: CCL11,SCYA11

Alternative Names : C-C motif chemokine 11, Small-inducible cytokine A11

Expression Region : 24-97aa

AA Sequence : GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDICADPKKKWVQD SMKYLDQKSP TPKP

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 8.4 kDa

Storage Buffer : Lyophilized from a 0.2 ?m filtered 20 mM PB, pH 7.4, 150 mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.

Function : In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Intercrine beta (chemokine CC) family

Tissue Specificity :

Paythway : Chemokinesignalingpathway

Uniprot ID : P51671