Product Description
Recombinant Human Fibroblast growth factor 4 protein (FGF4) (Active) is available at Gentaur for Next week Delivery.
Gene Name: FGF4,HST,HSTF1,KS3
Alternative Names : FGF-4, HST, HST-1, HSTF-1, Heparin-binding growth factor 4
Expression Region : 25-206aa
AA Sequence : GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
Sequence Info : Partial
Tag Info : Tag-Free
Theoretical MW : 19.8 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4, 300 mM NaCl
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by thymidine uptake assay using FGFreceptors transfected BaF3 cells is less than 0.5 ng/ml, corresponding to a specific activity of ? 2.0 × 106 IU/mg.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Cancer
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. {ECO:0000269|PubMed:8663044}.
Function : Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Heparin-binding growth factors family
Tissue Specificity :
Paythway : MAPKsignalingpathway
Uniprot ID : P08620