Recombinant Human Interleukin-17F protein (IL17F) (Active)

Product Description

Recombinant Human Interleukin-17F protein (IL17F) (Active) is available at Gentaur for Next week Delivery.

Gene Name: IL17F

Alternative Names : IL-17F,

Expression Region : 31-163aa

AA Sequence : M+RKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 30.1 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/ml, corresponding to a specific activity of ? 5.0 × 104 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.

Function : Ligand for IL17RA and IL17RC

Involvement in disease : Candidiasis, familial, 6 (CANDF6)

Subcellular location : Secreted

Protein Families : IL-17 family

Tissue Specificity : Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.

Paythway : IL-17signalingpathway

Uniprot ID : Q96PD4