Recombinant Human Interleukin-2 protein (IL2) (Active)

Product Description

Recombinant Human Interleukin-2 protein (IL2) (Active) is available at Gentaur for Next week Delivery.

Gene Name: IL2

Alternative Names : IL-2, TCGF, Aldesleukin

Expression Region : 21-153aa

AA Sequence : APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 15.4 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 5.0

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 × 107 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Function : Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Involvement in disease : A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

Subcellular location : Secreted

Protein Families : IL-2 family

Tissue Specificity :

Paythway : Jak-STATsignalingpathway

Uniprot ID : P60568