Recombinant Human Interleukin-31 protein (IL31) (Active)

Product Description

Recombinant Human Interleukin-31 protein (IL31) (Active) is available at Gentaur for Next week Delivery.

Gene Name: IL31

Alternative Names : IL-31,

Expression Region : 24-164aa

AA Sequence : SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 15.8 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The specific activity is determined by inducing STAT3 activation using human U-87 MG cells. 5 ng/mL of rHuIL-31 can effectively induce STAT3 activation.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269|PubMed:15184896}.

Function : Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR

Involvement in disease :

Subcellular location : Secreted

Protein Families :

Tissue Specificity : Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.

Paythway :

Uniprot ID : Q6EBC2