Product Description
Recombinant Human Lymphotactin protein (XCL1) (Active) is available at Gentaur for Next week Delivery.
Gene Name: XCL1,LTN,SCYC1
Alternative Names : ATAC, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1
Expression Region : 23-114aa
AA Sequence : GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG
Sequence Info : Partial
Tag Info : Tag-Free
Theoretical MW : 10.2 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Chemotactic activity for lymphocytes but not for monocytes or neutrophils.
Function : Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Intercrine gamma family
Tissue Specificity : Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
Paythway : Chemokinesignalingpathway
Uniprot ID : P47992