Recombinant Human Melanoma-derived growth regulatory protein (MIA) (Active)

Product Description

Recombinant Human Melanoma-derived growth regulatory protein (MIA) (Active) is available at Gentaur for Next week Delivery.

Gene Name: MIA

Alternative Names : Melanoma inhibitory activity protein,

Expression Region : 25-131aa

AA Sequence : GPMPKLADRK LCADQECSHP ISMAVALQDY MAPDCRFLTI HRGQVVYVFS KLKGRGRLFW GGSVQGDYYG DLAARLGYFP SSIVREDQTL KPGKVDVKTD KWDFYCQ

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 12.1 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using human A375 cell line is less than 5 ?g/ml, corresponding to a specific activity of ? 200 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.

Function : Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.

Involvement in disease :

Subcellular location : Secreted

Protein Families : MIA/OTOR family

Tissue Specificity : All malignant melanoma cell lines tested and infrequently in glioma cell lines.

Paythway :

Uniprot ID : Q16674