Product Description
Recombinant Human Neurotrophin-4 protein (NTF4) (Active) is available at Gentaur for Next week Delivery.
Gene Name: NTF4,NTF5
Alternative Names : NT-4, NT-5, Neutrophic factor 4
Expression Region : 81-210aa
AA Sequence : M+GVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 28.1 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 5.5
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Neuroscience
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Target-derived survival factor for peripheral sensory sympathetic neurons.
Function : Target-derived survival factor for peripheral sensory sympathetic neurons.
Involvement in disease : Glaucoma 1, open angle, O (GLC1O)
Subcellular location : Secreted
Protein Families : NGF-beta family
Tissue Specificity : Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
Paythway : MAPKsignalingpathway
Uniprot ID : P34130