Recombinant Human Nuclear receptor subfamily 1 group I member 3 (NR1I3), partial

Product Description

Recombinant Human Nuclear receptor subfamily 1 group I member 3 (NR1I3), partial is available at Gentaur for Next week Delivery.

Gene Name: NR1I3

Alternative Names : Constitutive activator of retinoid response;Constitutive active responseConstitutive androstane receptor;CAROrphan nuclear receptor MB67

Expression Region : 2-351aa

AA Sequence : ASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEIC

Sequence Info : Partial

Tag Info : N-terminal 6xHis-SUMO-tagged

Theoretical MW : 55.7 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Transcription

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Binds and transactivates the retinoic acid response elents that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive elent module of the human CYP2B6 gene and the CYP3A4 xenobiotic response elent.

Function : Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.

Involvement in disease :

Subcellular location : Nucleus, Cytoplasm, Cytoplasm, cytoskeleton

Protein Families : Nuclear hormone receptor family, NR1 subfamily

Tissue Specificity : Predominantly expressed in liver.

Paythway :

Uniprot ID : Q14994