Recombinant Human Perilipin-1 (PLIN1), partial

Product Description

Recombinant Human Perilipin-1 (PLIN1), partial is available at Gentaur for Next week Delivery.

Gene Name: PLIN1

Alternative Names : Lipid droplet-associated protein

Expression Region : 411-496aa

AA Sequence : EPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRV

Sequence Info : Partial

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 11.2 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cardiovascular

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.

Function : Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.

Involvement in disease : Lipodystrophy, familial partial, 4 (FPLD4)

Subcellular location : Endoplasmic reticulum, Lipid droplet

Protein Families : Perilipin family

Tissue Specificity : Adipocytes.

Paythway : PPARsignalingpathway

Uniprot ID : O60240