Product Description
Recombinant Human Protein BEX3 (NGFRAP1) is available at Gentaur for Next week Delivery.
Gene Name: NGFRAP1
Alternative Names : Brain-expressed X-linked protein 3Nerve growth factor receptor-associated protein 1Ovarian granulosa cell 13.0KDA protein HGR74p75NTR-associated cell death executor
Expression Region : 1-111aa
AA Sequence : MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP
Sequence Info : Full Length
Tag Info : N-terminal 6xHis-tagged
Theoretical MW : 15 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Apoptosis
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death . May play an important role in the pathogenesis of neurogenetic diseases.
Function : May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Involvement in disease :
Subcellular location : Nucleus, Cytoplasm
Protein Families : BEX family
Tissue Specificity : Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Paythway : Neurotrophinsignalingpathway
Uniprot ID : Q00994