Recombinant Human Sclerostin domain-containing protein 1 (SOSTDC1)

Product Description

Recombinant Human Sclerostin domain-containing protein 1 (SOSTDC1) is available at Gentaur for Next week Delivery.

Gene Name: SOSTDC1

Alternative Names : Ectodermal BMP inhibitor;EctodinUterine sensitization-associated gene 1 protein;USAG-1

Expression Region : 24-206aa

AA Sequence : FKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSNTGLDRNTRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESMSPAKPVQHHRERKRASKSSKHSMS

Sequence Info : Full Length of Mature Protein

Tag Info : N-terminal GST-tagged

Theoretical MW : 47.8 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling . Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.1 Publication

Function : May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Sclerostin family

Tissue Specificity : Highly expressed in kidney and weakly in lung.

Paythway :

Uniprot ID : Q6X4U4